Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
CARD8 antisense RNA 1 (CARD8-AS1)
- Target
- CARD8-AS1
- Molecular classification
- Other (Long non-coding RNA)
01
Overview
**CARD8 antisense RNA 1 (CARD8-AS1)** is a long non-coding RNA (lncRNA) located on chromosome 19, adjacent to the gene encoding caspase recruitment domain family member 8 (CARD8)[1]. While the CARD8 protein is involved in inflammation and immune response, CARD8-AS1 itself has no known protein-coding potential and is classified as a non-coding RNA. It has been proposed to play a regulatory or biomarker role in diseases such as leukemia, lymphoma, and possibly neuroblastoma, though its specific biological function and therapeutic potential are not well established. Its expression may sometimes result from transcriptional noise due to proximity to the CARD8 gene, rather than reflecting a defined functional role[1]. There is no evidence that CARD8-AS1 is a therapeutic target such as a receptor, enzyme, transporter, or transcription factor.
- Other names
- LOC100505812AC008392.1CARD8-AS1
02
Biological functions
Immune response (potential)Possible biomarker for leukemia/lymphoma
03
Disease associations
Cancer (leukemia, lymphoma)Possible role in neuroblastoma
04
Biomarkers
LOC100505812 is suggested as a biomarker for leukemia/lymphoma[1]
Beyond the preview
Go deeper on CARD8 antisense RNA 1 (CARD8-AS1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on CARD8 antisense RNA 1 (CARD8-AS1).