Cardiac Ion-Channel Protein

Cardiac ion-channel proteins are integral membrane proteins that form pores in the membranes of cardiac cells, allowing selective passage of ions such as sodium (Na⁺), potassium (K⁺), calcium (Ca²⁺), and chloride (Cl⁻). These channels are essential for generating and propagating the cardiac action potential, which underlies the rhythmic contraction and relaxation of heart muscle. Mutations or dysfunctions in cardiac ion-channel genes/proteins can cause arrhythmias due to altered excitability or conduction properties.

Other names

Cardiac ion channelHeart ion channel

Modulation of ion flow across cardiac cell membranes, affecting action potential duration and conduction velocity.