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Cardiac Myosin (None)

Target: None
Molecular classification: Myosin II, Molecular Motor Protein

Overview

Cardiac myosin is a molecular motor protein essential for heart muscle contraction. It belongs to the myosin II family, which are two-headed, filament-forming proteins. Cardiac myosin is specifically adapted to power the rhythmic contractions of the heart, playing pivotal roles not only in force generation but also in cardiac development, regulation, and mechanotransduction.

Mechanism of action

Modulation of cardiac myosin activity (contractility)

Biological functions

Muscle ContractionForce GenerationATP HydrolysisMechanotransductionCardiac Development

Disease associations

Hypertrophic Cardiomyopathy (HCM)Dilated CardiomyopathyHeart FailureArrhythmias

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