Carnitine palmitoyltransferase 2 pseudogene (CPT2P)

The carnitine palmitoyltransferase 2 pseudogene is a nonfunctional genomic DNA sequence with high similarity to the protein-coding CPT2 gene, which encodes the mitochondrial enzyme carnitine palmitoyltransferase 2 involved in fatty acid oxidation. Pseudogenes such as this retain substantial sequence homology to their parent genes but have accrued mutations (such as stop codons or frameshifts) that prevent synthesis of a functional protein product. Most annotated pseudogenes—including this one—serve no known physiological function, though a growing number can have regulatory roles at the RNA level in some contexts[1][3][4][5]. The CPT2 pseudogene is not currently recognized as a therapeutic target, disease biomarker, or drug-interaction partner. This pseudogene may be annotated in reference genome databases and could, by sequence similarity, occasionally confound assays targeting the functional CPT2 gene, but has no established function or disease association[3]. No evidence suggests therapeutic targeting, clinical significance, or functional interaction for ENSG00000277397. If structured information for drug targets, mechanisms, or disease roles is needed, the protein-coding CPT2 gene (not its pseudogene) should be referenced.

Other names

Carnitine palmitoyltransferase II pseudogeneCPT2 pseudogene