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Target intelligence / Profile preview
Casein kinase 1 gamma 2 antisense RNA 1 (CSNK1G2-AS1)
- Target
- CSNK1G2-AS1
- Molecular classification
- Long non-coding RNA, Other
01
Overview
Casein kinase 1 gamma 2 antisense RNA 1 (CSNK1G2-AS1) is a long non-coding RNA highly expressed in the testis and downregulated in TGCTs, where it regulates migration, invasion, apoptosis, EMT, and AKT signaling. Its methylation state correlates with TGCT prognosis.
- Other names
- C19orf34MGC39696Casein kinase 1 gamma 2 antisense RNA 1CSNK1G2 antisense RNA 1CSNK1G2 antisense gene protein 1CSNK1G2-AS1CSNK1G2 antisense RNA 1 (non-protein coding)
02
Mechanism of action
Not applicable; there are currently no drugs known to target CSNK1G2-AS1
03
Biological functions
Regulation of gene expressionPromotes cell migration and invasionInhibits apoptosisModulates EMTInfluences AKT signaling
04
Disease associations
CancerSpermatogenesisTesticular germ cell tumor
05
Biomarkers
CSNK1G2-AS1 methylation statusCSNK1G2-AS1 expression levels
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