Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Casein kinase 2 alpha prime subunit (CK2α′)
- Target
- CK2α′
- Molecular classification
- Enzyme, Protein Kinase, Serine/threonine-protein kinase, Casein Kinase II family
01
Overview
Casein kinase 2 alpha prime subunit (CK2α′) is a catalytic subunit of the serine/threonine protein kinase casein kinase 2 (CK2). It is involved in various cellular processes including cell cycle control, DNA repair, and regulation of circadian rhythm. Dysregulation has been linked to tumorigenesis due to its role in protecting mutated cells from apoptosis.
- Other names
- Casein kinase II alpha prime polypeptide subunitCK₂-A₂CSNK₂A₂
02
Mechanism of action
Inhibition of serine/threonine protein kinase activity
03
Biological functions
Cell cycle progressionDNA repairRegulation of circadian rhythmSpindle assembly checkpoint during mitosisPhosphorylation
04
Disease associations
Tumorigenesis
05
Safety considerations
Essential for cell survival; knockout models are not viable.Dysregulation linked to tumorigenesis
06
Interacting drugs
Naphthyridine-based compounds
1 more in the full profile.
Beyond the preview
Go deeper on Casein kinase 2 alpha prime subunit (CK2α′).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Casein kinase 2 alpha prime subunit (CK2α′).