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Caspase 1 pseudogene 2 (CASP1P2) is a human pseudogene located on chromosome 11, annotated by NCBI Gene ID: 440067. It is a non-protein-coding genomic segment that shares sequence similarity with the functional caspase 1 gene. Unlike caspase 1, which is an active cysteine-aspartic acid protease driving apoptosis and inflammatory cytokine maturation, CASP1P2 does not encode an active enzyme and is not known to have a direct biological function nor a role in disease, nor is it considered a therapeutic target[2].
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