Target intelligence / Profile preview

Catalase (n/a)

Target: n/a
Molecular classification: Enzyme, Oxidoreductase, Heme enzyme

Overview

Catalase is a ubiquitous enzyme found in nearly all living organisms exposed to oxygen. Its primary function is to catalyze the decomposition of hydrogen peroxide (H₂O₂), a potentially harmful byproduct of metabolic processes, into water (H₂O) and oxygen (O₂). This reaction protects cells from oxidative damage caused by reactive oxygen species (ROS).

Other names: CATEC 1.11.1.6

Mechanism of action

Catalyzes the decomposition of hydrogen peroxide into water and oxygen. The catalytic cycle involves the formation of Compound I and subsequent reduction back to the resting state.

Biological functions

Antioxidant defenseHydrogen peroxide decompositionReactive oxygen species (ROS) detoxification

Disease associations

Diabetes mellitus complicationsNeurodegenerative disordersCancer progression

Safety considerations

Copper deficiency reduces catalase levels.Inhibition by heavy metals.pH sensitivity.

Interacting drugs

Copper(II) sulfate (inhibitor)

2 more in the full profile.

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