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Catfish Parvalbumin (N/A)
- Target
- N/A
- Molecular classification
- Calcium-binding protein, EF-hand protein, Parvalbumin
01
Overview
Catfish parvalbumin is a muscle protein and the major allergen responsible for IgE-mediated allergic reactions to catfish. While not yet fully characterized at the molecular level for catfish specifically, it is presumed to be a parvalbumin isoform, a calcium-binding EF-hand protein. It exhibits cross-reactivity with parvalbumins from other finned fish, posing a risk of allergic reactions in individuals sensitized to other fish species. Exposure can occur through ingestion or inhalation of aerosolized proteins during cooking.
- Other names
- Catfish allergenFish allergen (catfish)Parvalbumin (catfish)
02
Mechanism of action
N/A
03
Biological functions
Calcium bufferingMuscle relaxationSignal transduction (calcium-dependent)
04
Disease associations
Food allergyIgE-mediated hypersensitivity
05
Safety considerations
AnaphylaxisCross-reactivity with other finned fishAirborne exposure during cooking
06
Biomarkers
IgE antibodies specific to catfish protein
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