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Target intelligence / Profile preview
CAVIN2 and TMEFF2 antisense RNA 1 (CAVIN2-AS1)
- Target
- CAVIN2-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA, Other
01
Overview
CAVIN2-AS1 (ENSG00000303245) is a long non-coding RNA (lncRNA) gene located antisense to the SDPR (serum deprivation response) locus. The SDPR gene encodes a protein involved in caveolae formation and signal transduction, with known tumor suppressor activity especially in breast and lung cancer. While antisense transcription is known to regulate sense gene expression via modulation of chromatin state and transcriptional dynamics in other contexts, the specific biological roles or clinical relevance of the CAVIN2-AS1 transcript have not been established in published literature. It is not recognized as a therapeutic target, and there is no documentation of interacting drugs, disease association, or use as a biomarker. The entry may represent an incomplete, poorly annotated, or non-canonical target.
- Other names
- CAVIN2-AS1CAVIN2 and TMEFF2 antisense RNA 1novel transcript, antisense to SDPR
02
Biological functions
Not well characterized; likely regulation of SDPR gene expression through antisense activityPossible involvement in chromatin modification or transcriptional regulation as seen in other antisense lncRNAsOther
03
Disease associations
Not definitively established; SDPR itself acts as a tumor suppressor in cancers including breast, lung, kidney, prostate, and sarcoma, but the specific role of the antisense transcript is unknownOther
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