CCDC148 antisense RNA 1 (CCDC148-AS1)

CCDC148 antisense RNA 1 (CCDC148-AS1) is a long non-coding RNA (lncRNA) located on chromosome 11 and is approximately 1,500 nucleotides in length[2]. It is classified as an antisense RNA, meaning it is complementary to the mRNA of the CCDC148 gene, and it does not encode a protein[2][3]. CCDC148-AS1 is expressed in several tissues, including the brain, heart, and liver, and interacts with RNA-binding proteins such as hnRNPK, suggesting a regulatory role[2]. Although its precise biological function remains largely uncharacterized, CCDC148-AS1 is implicated in the regulation of gene expression at the transcriptional, post-transcriptional, and possibly epigenetic levels, with roles suggested in controlling cell proliferation, apoptosis, and migration[2]. Like other antisense lncRNAs, it could potentially be involved in cancer-related pathways; however, specific disease associations or therapeutic targeting of CCDC148-AS1 have not been definitively established[4][2][3]. No drugs, biomarkers, or specific safety concerns related to CCDC148-AS1 are currently known.

Other names

CCDC148 antisense RNA 1 (non-protein coding)tmp_locus_26CCDC148-AS1