CCR4 carbon catabolite repression 4-like pseudogene (ENSG00000256533)

The CCR4 carbon catabolite repression 4-like pseudogene (ENSG00000256533, LOC100422382) is a human genomic sequence similar in structure to CCR4 family genes but is classified as a pseudogene, implying that it does not encode a functional protein. This distinguishes it from true CCR4 family members, such as CNOT6, CNOT6L, ANGEL1, ANGEL2, etc., which participate in mRNA metabolism, cell cycle regulation, and are sometimes implicated in cancer[1][5]. While true CCR4 proteins (e.g., CCR4d/ANGEL2) are involved in cell cycle arrest, p21 regulation, and may have a role in carcinogenesis[1], this specific pseudogene lacks such activity and is not considered a classical molecular target nor implicated in human disease or drug action. The entry may be included in databases for genomic annotation or evolutionary studies but has no established role as a functional receptor, enzyme, or drug target. If you are seeking information on active CCR4 family proteins (such as CCR4d or ANGEL2), these are distinct, functional molecules involved in mRNA metabolism and cell cycle regulation[1][3][5]. The pseudogene described here is not functionally equivalent and should not be considered a therapeutic target.

Other names

CCR4 carbon catabolite repression 4-like (S. cerevisiae) pseudogeneLOC100422382ENSG00000256533

Not applicable. No mechanism of action reported, as it does not encode a functional protein.