CD109 antisense RNA 1 (CD109-AS1)

CD109-AS1 (CD109 antisense RNA 1) is a long non-coding RNA identified as an epigenetically regulated molecule with roles in tumor biology. In glioblastoma cells, CD109-AS1 expression promotes proliferation, migration, invasion, and immune evasion. Knockdown of CD109-AS1 reduces proliferation, migration, and invasiveness of tumor cells and downregulates key immune regulatory proteins such as FOXP3, CTLA-4, and PD-L1, pointing to its impact on immunosuppressive signaling in cancer. CD109-AS1 is considered a novel biomarker for glioma immune evasion, but it is not a classical receptor, enzyme, transporter, or current drug target. If you are seeking information about the protein-coding gene CD109 (CD109 molecule), which is a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein involved as a co-receptor for TGF-β and regulator of inflammation, please clarify, as these are distinct entities with different biological roles. Note: - CD109-AS1 is a non-coding RNA (not a protein) and is therefore not part of classic molecular classification families like "G protein-coupled receptor," "Ion channel," "Enzyme," or "Transporter." - Its primary research context is *biomarker discovery* and *functional genomics* within cancer biology, especially glioma immunity.

Other names

CD109-AS1CD109 Antisense RNA 1lncRNA CD109-AS1