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CD177 molecule pseudogene 1 (CD177P1)

Target: CD177P1
Molecular classification: Other

Overview

CD177 molecule pseudogene 1 (CD177P1) is a non-functional genetic element adjacent to the CD177 gene on human chromosome 19. The pseudogene is not translated into a functional protein. Instead, it is involved in genetic events that can result in the "CD177-null" phenotype in certain individuals, where exons from CD177P1 replace their counterparts in the functional CD177 gene through gene conversion, introducing a premature stop codon. This loss of CD177 protein surface expression can affect neutrophil function; however, the pseudogene itself does not have a direct biological or therapeutic role.

Other names: CD177P1CD177 pseudogene 1

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