Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
CD1d molecule (CD1d)
- Target
- CD1d
- Molecular classification
- MHC class I-like molecule, Glycoprotein
01
Overview
CD1d is a non-polymorphic MHC class I-like molecule that presents lipid and glycolipid antigens to iNKT cells. This interaction triggers iNKT cell activation, leading to the release of cytokines and cytotoxic activity, influencing both innate and adaptive immunity. CD1d plays a crucial role in various diseases, including asthma, cancer, infectious diseases, and autoimmune disorders, making it a potential therapeutic target.
- Other names
- CD1D antigenCluster of Differentiation 1d
02
Mechanism of action
Agonist of iNKT cell receptor via CD1d presentation
03
Biological functions
Antigen presentationLipid antigen presentationiNKT cell activationImmune modulation
04
Disease associations
AsthmaCancerInfectionAutoimmunityMetabolic disordersInflammatory diseasesCrohn’s diseaseUlcerative colitis
05
Safety considerations
Potential for cytokine stormRisk of autoimmunityOff-target effects on other immune cells
06
Interacting drugs
alpha-galactosylceramide (α-GalCer)
Beyond the preview
Go deeper on CD1d molecule (CD1d).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on CD1d molecule (CD1d).