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Target intelligence / Profile preview
CD300c molecule (CD300C)
- Target
- CD300C
- Molecular classification
- Receptor, Immunoglobulin superfamily protein, Type I transmembrane protein
01
Overview
CD300c molecule is an activating member of the CD300 family of immunoglobulin-like type I transmembrane receptors predominantly expressed on monocytes, neutrophils, and subsets of T and B lymphocytes. Like related CD300 family molecules, CD300C participates in the modulation of immune responses by recognizing phospholipids (such as those exposed on dead or apoptotic cells) and transmitting signals that influence leukocyte activation, cytokine release, and other immune functions. CD300C may have roles in inflammatory, infectious, and allergic diseases, and represents a potential target for diagnostic and therapeutic strategies in immune-mediated conditions.
- Other names
- CMRF35 antigenCMRF35AIGSF16LIRCLM-6CMRF-35ACMRF35Immunoglobulin superfamily member 16CD300 antigen-like family member C
02
Biological functions
Signal transductionModulation of immune responseRegulation of leukocyte activation
03
Disease associations
InflammationInfectionCancer (potential diagnostic/therapeutic marker)Autoimmunity (related to immune disorders)Other (participation in allergic and inflammatory conditions)
04
Safety considerations
Potential immune dysregulationOff-target effects in immunotherapiesSpecific challenges and adverse effects are not well characterized for CD300C
05
Biomarkers
CD300C is not a widely adopted biomarker, but other family members (e.g., CD300a) are studied as potential markers in immune and allergic diseases; CD300C may have emerging relevance
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