Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
CD47 antigen (CD47)
- Target
- CD47
- Molecular classification
- Transmembrane glycoprotein, Immunoglobulin superfamily
01
Overview
CD47 antigen (also known as integrin-associated protein, IAP) is a widely expressed transmembrane glycoprotein that plays a critical role in immune regulation, cell signaling, and cancer biology. It acts as a "don't eat me" signal to macrophages by binding to SIRPα, inhibiting phagocytosis. Overexpressed in various tumor types, it is a target for novel immunotherapies.
- Other names
- Integrin-associated proteinIAPRh-related antigen
02
Mechanism of action
Blockade of CD47/SIRPα interaction, disruption of post-translational modifications
03
Biological functions
Immune regulationApoptosisCell proliferationCell adhesionCell migrationAngiogenesisPlatelet activationInsulin secretion
04
Disease associations
Cancer
05
Safety considerations
Anemia
06
Interacting drugs
Anti-CD47 antibodies
3 more in the full profile.
Beyond the preview
Go deeper on CD47 antigen (CD47).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on CD47 antigen (CD47).