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CDC14 cell division cycle 14 C-like pseudogene (ENSG00000225705) is a non-coding DNA sequence in the human genome with similarity to the CDC14C gene but does not produce a functional protein product[2]. As a pseudogene, it is a remnant of gene duplication or retrotransposition and typically does not play an active role in biological pathways or serve as a therapeutic target. No evidence indicates role in cell signaling, enzymatic activity, or direct disease causation. Its name derives from sequence similarity to CDC14C, a member of the CDC14 dual-specificity phosphatase family, whose true functional homologs are involved in cell cycle regulation and differentiation in humans and other species[1][2][3]. Notable clarification: - The provided name includes "novel pseudogene similar to CDC14 cell division cycle 14 homolog C CDC14C" with the gene ID ENSG00000225705. This is not a functional enzyme, receptor, or any pharmacologically relevant target, and thus should not be considered a therapeutic target. - In gene-centric databases, such as GeneCards and Ensembl, this entry is labeled as a **pseudogene** and specifically noted as non-coding and lacking an experimentally-validated biological function or druggability[2]. - The "is_incorrect" flag is marked **true** because: - It is not an established target for therapeutic intervention. - The entry may be the result of an automated annotation or a misinterpretation of gene homology. - All available evidence supports that it is not a functional gene product but a genomic fossil.
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