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Target intelligence / Profile preview
Cdc25C-associated kinase 1 (None)
- Target
- None
- Molecular classification
- Enzyme, Serine/threonine protein kinase
01
Overview
Cdc25C-associated kinase 1 (C-Tak1) is a serine/threonine protein kinase that phosphorylates Cdc25C on Ser216, promoting 14-3-3 binding and cytoplasmic sequestration, thereby regulating G2/M transition in the cell cycle. It is a potential therapeutic target for cancer.
- Other names
- CTak1
02
Mechanism of action
Kinase inhibitor
03
Biological functions
Cell cycleCell cycle controlCheckpoint regulation
04
Disease associations
Cancer
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