Target intelligence / Profile preview

CDC28 protein kinase regulatory subunit 1B pseudogene 4 (CKS1BP4)

Target
CKS1BP4
Molecular classification
Pseudogene
01

Overview

CDC28 protein kinase regulatory subunit 1B pseudogene 4 (CKS1BP4) is a processed pseudogene in the human genome that shares sequence similarity with the functional CKS1B gene, which encodes a CDK regulatory protein important for cell cycle progression[1][6][7][8]. CKS1BP4 itself does not appear to produce protein, and no biological function or disease association has been firmly established for this locus. As with other processed pseudogenes, there is theoretical potential for regulatory function at the RNA level (such as miRNA sponging), but such roles have not been demonstrated for CKS1BP4 specifically[4][10]. Key facts: - CKS1BP4 is distinct from CKS1B, the latter being a functional gene encoding a cell cycle regulatory protein[12]. - No evidence suggests CKS1BP4 is a receptor, enzyme, transporter, or transcription factor. - There are no reported drugs, biomarkers, or clinical safety concerns related to CKS1BP4. If searching for the functional cell cycle regulator, see "CDC28 protein kinase regulatory subunit 1B" (CKS1B), not CKS1BP4.

02

Mechanism of action

Not applicable

03

Biological functions

No known functional protein product[1][6][7].As a pseudogene, potential minor roles may include regulation at the RNA level through competing endogenous RNA (ceRNA) activity, but such functions are not characterized for this specific gene[4][10].
04

Disease associations

None documented for this pseudogene; pseudogenes in general are rarely direct disease drivers, though they can be implicated in regulatory effects[4][10].

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