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The CDGSH iron sulfur domain pseudogene (ENSG00000257405) is a DNA sequence in the human genome that resembles a member of the CDGSH iron-sulfur domain-containing protein family but does not produce a functional protein due to genetic changes[2][4]. It was likely formed by gene duplication or retrotransposition and forms part of the non-coding "junk" DNA. While the functional CDSDH proteins (e.g., CISD1/mitoNEET) play key roles in mitochondrial iron homeostasis and redox biology, this pseudogene itself lacks coding potential and biological activity[1][2][4][5].
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