CDK2-associated protein 1 pseudogene

CDK2-associated protein 1 pseudogene (ENSG00000213774, LOC124905951) refers to a **pseudogene** homologous to the *CDK2AP1* (cyclin-dependent kinase 2-associated protein 1) locus. **Pseudogenes** are genomic elements derived from once-functional genes, typically harboring mutations that prevent them from producing functional protein products. Unlike the protein-coding *CDK2AP1* gene (officially "cyclin-dependent kinase 2-associated protein 1"), which regulates cell cycle progression and epigenetic programs, the pseudogene form usually does **not encode an active protein** and is *not considered a therapeutic target*. However, like other pseudogenes, it may produce noncoding RNA transcripts that can act as molecular sponges, siRNAs, or regulators of parental gene expression, potentially influencing disease pathways indirectly, particularly in cancer contexts, but this role is not well defined or targeted clinically[4][2][6][8]. **Rationale and ambiguity resolution:** - "CDK2-associated protein 1 pseudogene" (ENSG00000213774) is distinct from protein-coding *CDK2AP1* and lacks protein function; it is a **noncoding pseudogene**[4][2]. - It is not recognized as a drug target, receptor, enzyme, transporter, or transcription factor. - No drugs, mechanisms of action, biomarkers, or safety considerations apply to this pseudogene. - Role, if any, is at the RNA level via gene regulation, not direct molecular targeting[4][2][6]. If you intended the functional, protein-coding gene, that would be *cyclin-dependent kinase 2-associated protein 1 (CDK2AP1)* or *DOC1* (aliases: DORC1, ST19, doc-1, p12DOC-1)[1][3][7][9], which **is not the same** as this pseudogene. If clarification or the protein-coding gene profile is needed, please specify.

Other names

ENSG00000213774LOC124905951cyclin dependent kinase 2 associated protein 1 pseudogene