CDON pseudogene 1 (CDONP1)

CDON pseudogene 1 (CDONP1) is annotated as a pseudogene in the human genome. Pseudogenes are genomic sequences similar to known genes but are typically non-functional due to mutations preventing their expression as functional proteins[2][4]. Unlike its protein-coding counterpart CDON—which acts as a Hedgehog pathway co-receptor and has defined roles in cell differentiation, embryonic development, and disease—the pseudogene variant CDONP1 does not encode a functional cell-surface receptor and is not involved in signal transduction or cellular adhesion[2][3][5]. Pseudogenes can sometimes play regulatory roles through transcriptional interference, RNA binding, or as competitive endogenous RNAs (ceRNAs), but there is currently no evidence for such a function for CDONP1 specifically[2]. It is not considered a therapeutic target, receptor, or biomarker. Clarification / Caution: - is_incorrect = true because CDONP1 is a pseudogene, not a drug target, receptor, or enzyme. Literature and database references to drug targets for "CDON pseudogene 1" are likely mistaken, or are confusing it with the protein-coding CDON gene[3][5]. - If what is desired is information about the *functional, druggable receptor* CDON (Cell adhesion molecule-related/down-regulated by oncogenes), then the correct canonical target would be "CDON (Cell adhesion molecule-related/down-regulated by oncogenes receptor)"[3][5][1]. - Pseudogenes generally are not assigned biological functions, roles in disease, or mechanisms of drug action, unless there is explicit experimental evidence—which is currently lacking for CDONP1[2][4]. If your query refers to the functional receptor (CDON), please clarify, as this entry concerns only the pseudogene.

Other names

Cdon homolog pseudogenecell adhesion associated, oncogene regulated pseudogeneCDONP1