CDRT15 pseudogene 11 (CDRT15P11)

CDRT15 pseudogene 11 (CDRT15P11) is a predicted human pseudogene, related to CDRT15, and is located within a region of low copy repeats (LCRs) in the human genome. Pseudogenes are typically non-functional as protein-coding genes, but may have regulatory roles through their RNA transcripts. For CDRT15P11, there is no evidence of a protein product or established biological function. Multiple similar pseudogenes map to different genomic regions, contributing to the structural complexity of genomic repeat regions (including regions associated with conditions such as Smith-Magenis syndrome). Only a few paralogs of CDRT15 show minimal RNA expression in adult tissue, with higher embryonic expression, but functional relevance (if any) of CDRT15P11 is unresolved. There is no indication CDRT15P11 is a receptor, enzyme, transporter, or other typical therapeutic target. The designation “CDRT15P11” denotes its status as a pseudogene; its sequence is similar to the functional CDRT15 gene, which itself encodes an unknown protein. There is no evidence for disease association, biomarker utility, or drug interactions for CDRT15P11. Pseudogenes as a class may have regulatory roles or be implicated in disease, but specific evidence for this gene is lacking. CDRT15 pseudogene 11 is a predicted human pseudogene related to CDRT15, not a therapeutic target, with no known biological or disease associations, drug interactions, or biomarker utility. Its presence highlights genomic repeat complexity and the potential, but unproven, regulatory functions of some pseudogenes.

Other names

CDRT15P11CDRT15 pseudogenevariants in genomic databases

None known