Target intelligence / Profile preview

CELF2 antisense RNA 1 (CELF2-AS1)

Target
CELF2-AS1
Molecular classification
Long non-coding RNA, Antisense RNA
01

Overview

CELF2 antisense RNA 1 (CELF2-AS1) is a long non-coding RNA (lncRNA) gene located on chromosome 10 (official symbol: CELF2-AS1, HGNC:23515, NCBI Gene ID: 414196). It acts as an antisense RNA overlapping the CELF2 gene, and is classified as an lncRNA rather than a traditional protein-coding gene or therapeutic target. According to genomic databases, it is predicted to be located in the extracellular region[4][7][8]. CELF2-AS1 has been linked via database annotation to "Developmental and epileptic encephalopathy 97"[7], but there is currently no strong evidence for direct disease causation or validated drug targeting. The biological function remains largely uncharacterized, though as an antisense lncRNA it is presumed to play a regulatory role in gene expression, possibly modulating the expression of the CELF2 gene or neighboring loci[6][7]. No approved drugs, clinical biomarkers, or therapeutics specifically interact with CELF2-AS1. Its status as a therapeutic target is not established, and the protein-coding potential is either absent or not demonstrated[6][7][8]. Summary: CELF2-AS1 is a long non-coding antisense RNA gene, not a canonical drug target or protein. Its function is not well-defined, but it is classified among regulatory lncRNAs that may influence gene expression. No interacting drugs, mechanisms of action, or clinical safety concerns are currently described.

Other names
C10orf31FLJ40494Em:AC026887.2CELF2-AS1CELF2 antisense gene protein 1
02

Biological functions

Likely involved in RNA regulation and potentially in gene expression regulation; specific functions unknown
03

Disease associations

Associated with "Developmental and epileptic encephalopathy 97"; the evidence base for other disease roles is limited and indirect

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