Celiac plexus nerve

The **celiac plexus** (commonly, but imprecisely referred to as "celiac plexus nerves") is a complex autonomic nerve plexus in the upper abdomen, located near the celiac trunk, where it serves as a central hub for both sympathetic (from greater and lesser splanchnic nerves) and parasympathetic (from the vagus nerves) fibers[1][3][4]. The celiac plexus supplies autonomic innervation to major abdominal organs including the stomach, liver, pancreas, spleen, kidneys, and proximal small intestine[1][4]. It conducts both motor and sensory signals, especially visceral pain from abdominal organs to the central nervous system[5]. Interventional procedures such as celiac plexus block or ablation are used clinically to control intractable abdominal pain, particularly from pancreatic cancer or chronic pancreatitis[3][5]. "Celiac plexus nerves" is an imprecise term; the correct target for interventions or mechanistic study is the whole celiac plexus, not individual nerves. **Note:** The requested target, "Celiac plexus nerves," is not the standard canonical form. The canonical form is "Celiac plexus," which refers to the autonomic plexus (a network of nerves and ganglia), not discrete molecular or single neuronal targets[1][3][4]. The "nerves" are components of this plexus but do not exist as distinct named entities for targeting in drug development or molecular targeting contexts. Thus, `is_incorrect` is set to true due to naming imprecision, although the plexus itself is a clinical target for intervention.

Other names

Celiac plexusSolar plexusCoeliac plexus

Block or ablation to interrupt pain signal transmission (neurolytic or anesthetic block of autonomic fibers)