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Target intelligence / Profile preview
Cell death-inducing DFFA-like effector B
- Molecular classification
- Other
01
Overview
CIDEB is a member of the CIDE family of proteins, involved in lipid metabolism and apoptosis. It plays a critical role in lipid droplet fusion and regulation, and is essential for HCV entry into hepatocytes. Loss-of-function mutations are protective against liver disease and obesity.
- Other names
- CIDEBCell death inducing DFFA like effector b
02
Biological functions
Lipid droplet fusionRegulation of lipid droplet sizePositive regulation of apoptotic processesLipid metabolismVLDL biogenesis/secretion
03
Disease associations
Hepatitis C Virus InfectionMetabolic DisordersLiver disease
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