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cell death-inducing DFFA-like effector c pseudogene

Molecular classification
Pseudogene
01

Overview

The **cell death-inducing DFFA-like effector c pseudogene** is a non-functional DNA sequence in the human genome that closely resembles the *cell death-inducing DFFA-like effector c* gene (CIDEC, also known as CIDE-3, CIDE3, or FSP27) but lacks the ability to encode a functional protein[1][3][9]. Pseudogenes typically arise through gene duplication or retrotransposition followed by the accumulation of disabling mutations[1]. While most pseudogenes are transcriptionally silent and considered non-functional, some can influence the expression of their functional relatives through regulatory RNA pathways[5]. For this specific pseudogene, there is currently no evidence for a direct biological or disease-related function, nor is it considered therapeutically actionable. If the intent was to refer to the **protein-coding gene** and potential therapeutic target, the correct entry would be "cell death-inducing DFFA-like effector c (CIDEC or CIDE-3)". The pseudogene should not be considered a therapeutic target.

Other names
CIDE-3 (applies to protein-coding gene, not specifically to pseudogene)CIDE3FSP27Fat-specific protein 27FLJ20871Cell death activator CIDE-3Cell death-inducing DFFA-like effector protein CCIDEC pseudogene
02

Biological functions

Regulation of gene expression (possible, as some pseudogenes can modulate parental gene expression at the RNA level by acting as competitive endogenous RNAs or miRNA decoys, but not established for all pseudogenes)[5][1]Other
03

Disease associations

Other (possible regulatory roles in disease, but this is not established for every pseudogene; parental gene associated with lipid metabolism dysfunction and metabolic disease, but not the pseudogene itself)[1][5][10]

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