Target intelligence / Profile preview

Cell death-inducing DNA fragmentation factor alpha-like effector C (CIDEC)

Target
CIDEC
Molecular classification
CIDE family protein, Lipid transferase
01

Overview

Cell death–inducing DNA fragmentation factor alpha-like effector C (CIDEC) is a protein primarily involved in lipid metabolism and adipocyte biology. It promotes unilocular lipid droplet formation by mediating lipid droplet fusion within adipocytes and acts as a regulator of adipocyte lipid metabolism, facilitating optimal energy storage. Dysregulation or altered expression of CIDEC has been implicated in several metabolic disorders, including obesity, type 2 diabetes, and non-alcoholic fatty liver disease. Alterations at the genomic locus containing CIDEC have been observed in some cancers, suggesting broader roles beyond metabolism alone.

Other names
FSP27Fat-specific protein 27
02

Biological functions

Lipid droplet formationAdipocyte lipid metabolism regulationApoptosisEnergy storage
03

Disease associations

ObesityType 2 diabetesNon-alcoholic fatty liver diseaseCancer

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