Cell death induction

"Cell death induction" is a general term describing the activation and regulation of molecular processes that lead to cellular demise, either through controlled (programmed) mechanisms (e.g., apoptosis, autophagy, necroptosis, ferroptosis, pyroptosis) or via accidental/unregulated processes[5][4][9]. Distinct signaling pathways and protein families regulate these processes, including caspases, Bcl-2 family proteins, death receptors (such as TNF receptor, Fas, DR4/5), and mitochondrial proteins. Cell death induction underlies normal physiological process (e.g., development, immune homeostasis) and is implicated in the pathogenesis and treatment of many diseases, but "cell death induction" itself is not a discrete molecular target and cannot be directly targeted by drugs—it represents an outcome or process involving many different potential therapeutic targets[5][9][7].

Other names

Programmed cell death inductioninduction of apoptosiscell death processcell death pathway activation