Target intelligence / Profile preview

Cell division and growth

Molecular classification
Other
01

Overview

"Cell division and growth" refers to the fundamental biological processes by which cells increase in number and size, enabling organismal development, tissue maintenance, and repair. This process is governed by the cell cycle—a series of regulated stages including interphase (G1, S, G2) where the cell grows and replicates its DNA, followed by mitosis (M phase), during which nuclear material divides equally into two daughter cells. Cytokinesis then separates the cytoplasm to complete cell division. These processes are tightly controlled by checkpoints that ensure proper DNA replication and integrity before progression to subsequent phases. Dysregulation of these mechanisms can lead to diseases such as cancer[1][2][3][4][5][6][7]. Note: "Cell division and growth" is not a specific molecule or receptor but rather describes a set of cellular processes involving many molecular targets such as cyclins, cyclin-dependent kinases (CDKs), checkpoint proteins like p53, enzymes involved in DNA replication (e.g., DNA polymerase), structural proteins for mitotic spindle formation (e.g., tubulin), among others[3]. For structured information on drug targets or receptors involved in these processes—such as "Cyclin-dependent kinase 1," "p53," or "Aurora kinase A"—a more specific molecular name should be provided. There is something wrong with this target entry because it does not refer to a single molecule or receptor but instead describes an entire class of biological events; therefore it cannot be mapped directly onto canonical target fields used for drug discovery databases.

Other names
Cell growth and divisionCell cycleMitosis and cell divisionCellular proliferation
02

Biological functions

Cell cycleCell proliferationGrowth regulationDNA replication
03

Disease associations

Cancer (dysregulation of cell division is a hallmark of cancer)Other (developmental disorders, tissue regeneration)

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