Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Cell division cycle 25A phosphatase (CDC25A)
- Target
- CDC25A
- Molecular classification
- Enzyme, Phosphatase, Dual-specificity phosphatase, CDC25 family
01
Overview
CDC25A is a dual-specificity protein phosphatase essential for cell cycle regulation. It activates cyclin-dependent kinases (CDKs) by removing inhibitory phosphate groups, promoting cell cycle progression at the G1/S and G2/M transitions. Overexpression of CDC25A is frequently observed in cancers, making it a target for therapeutic intervention. It regulates apoptosis.
- Other names
- M-phase inducer phosphatase 1Dual specificity phosphatase Cdc25ACDC25A2
02
Mechanism of action
Inhibition of CDC25A phosphatase activity; induction of degradation
03
Biological functions
Cell cycleCell proliferationApoptosis regulationG1/S transitionG2/M progression
04
Disease associations
Cancer
05
Safety considerations
Potential for off-target effects due to the role of CDC25A in normal cell cycle controlToxicity associated with cell cycle inhibition
06
Biomarkers
CDC25A expression levels in tumor tissue
Beyond the preview
Go deeper on Cell division cycle 25A phosphatase (CDC25A).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Cell division cycle 25A phosphatase (CDC25A).