Target intelligence / Profile preview

Cell Division Cycle Protein 25C (None)

Target: None
Molecular classification: Enzyme, Dual-specificity protein tyrosine phosphatase

Overview

Cdc25C phosphatase is a dual-specificity phosphatase crucial for cell cycle regulation, particularly in triggering mitosis. It dephosphorylates and activates CDK1, a key event for entry into M phase. Its activity is regulated by phosphorylation and ubiquitination, and it interacts with various proteins involved in cell cycle control. Cdc25C has been implicated in cancer and viral replication, and is a target for therapeutic intervention.

Other names: CDC25CM-phase inducer phosphatase 3

Mechanism of action

Inhibition of CDC25C phosphatase activity, leading to cell cycle arrest.

Biological functions

Cell cycleMitosis initiationDephosphorylationCDK1 activation

Disease associations

CancerViral Replication

Safety considerations

Potential for off-target effects due to structural similarity with other phosphatases.

Interacting drugs

NSC663284

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