Target intelligence / Profile preview

Cell Membrane

Molecular classification
Biological membrane, Phospholipid bilayer, Glycoprotein, Glycolipid, Other
01

Overview

The cell membrane, also known as the plasma membrane, is a biological membrane that surrounds the cytoplasm of all living cells. It acts as a selective barrier, controlling the movement of substances in and out of the cell. Its structure is primarily a phospholipid bilayer with embedded proteins and cholesterol. It plays critical roles in cell communication, structural support, and maintaining cell potential. While not a direct drug target itself, many drugs interact with its components.

Other names
Plasma membrane
02

Mechanism of action

Varies depending on the specific drug and target. Some drugs disrupt membrane integrity, while others bind to membrane-bound receptors or proteins to modulate cellular signaling.

03

Biological functions

Selective barrierCellular communicationStructural supportMaintenance of cell potentialRegulated transportHomeostasis
04

Disease associations

InfectionCancerOther
05

Safety considerations

Drug resistance (in bacteria)Off-target effects due to membrane similarity across cell typesMembrane toxicity
06

Interacting drugs

Antibiotics (membrane-disrupting)

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