Target intelligence / Profile preview

Cell Membrane Structure

Molecular classification: Lipid bilayer, Phospholipids, Lipopolysaccharides, Sterols

Overview

The cell membrane structure, encompassing the plasma and outer membranes, as well as the cell wall, is targeted by certain antimicrobial drugs to disrupt its integrity and function. This disruption leads to increased permeability, leakage of cellular contents, and ultimately cell death. These agents exploit differences in membrane composition between microbial cells (bacteria or fungi) and mammalian cells to achieve selective toxicity.

Other names: Plasma membraneOuter membraneCell wall

Mechanism of action

Disruption of membrane integrity leading to increased permeability, leakage of cellular contents, and cell death.

Biological functions

Selective permeabilityCellular integrityHomeostasisBarrier function

Disease associations

Infection

Safety considerations

Nephrotoxicity (Polymyxins)Reduced drug binding

Interacting drugs

Daptomycin

3 more in the full profile.

Beyond the preview

Go deeper on Cell Membrane Structure.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Cell Membrane Structure.

Explore the full profile