Cell proliferation and tissue regeneration pathway

"Cell proliferation and tissue regeneration pathway" is a descriptive term for a collection of distinct but interconnected signaling networks (including Wnt/β-catenin, MAPK/ERK, JAK/STAT, Notch, Hedgehog, Hippo-YAP, and others) that govern cell division, replacement, and differentiation during development, post-injury repair, and disease states. These pathways orchestrate cellular responses such as entry into the cell cycle, production of new cells from stem or progenitor pools, control of apoptosis (programmed cell death), and specification of tissue structure during repair. While precise modulation of these pathways is essential for healthy tissue maintenance and regeneration, their dysregulation is closely linked to pathological processes such as cancer, fibrotic disease, and impaired wound healing. Because this is not a single molecule, enzyme, receptor, or other standardized "target," but rather a general biological concept, drug development and therapeutic interventions focus on individual components within these networks.

Other names

Cell proliferation signaling pathwaysTissue regeneration signaling pathwaysRegenerative pathwaysProliferative signaling cascades