Cell proliferation process

Cell proliferation is a fundamental biological process in which cells grow and divide, producing two daughter cells from one original cell[5]. It is central to tissue growth, regeneration, development, and wound healing[5][7][1]. In multicellular organisms, cell proliferation is tightly regulated by cell cycle checkpoints and influenced by growth factors, nutrients, and internal signaling pathways such as cyclins, cyclin-dependent kinases (CDKs), p53, Rb, and various signal transduction networks (e.g., MAPK, AKT)[2][3][8]. Disruption of cell proliferation regulation leads to diseases including cancer and developmental disorders. Measuring cell proliferation is essential in biological research and is commonly done using biomarkers like PCNA, Ki-67, and BrdU incorporation[7]. Note: The term "cell proliferation process" refers to a biological process, not a druggable target such as a protein or receptor. For structured data, this entry should be flagged as incorrect/misclassified for target-centric applications.

Other names

cell growth and divisioncellular proliferation