Cell-cell communication

Cell–cell communication is the essential process by which cells in multicellular organisms transmit signals to each other. This communication is necessary for growth, development, differentiation, tissue and organ formation, and the ongoing regulation of physiology and homeostasis. Communication occurs via a variety of molecular mechanisms, including direct contact (e.g. through gap junctions or adhesion molecules), secreted chemical messengers (such as hormones and neurotransmitters), and the activation of cell-surface or intracellular receptors, which initiate downstream signaling pathways that control cellular responses. The disruption of cell–cell communication processes is linked to many diseases, including cancer, neurodegeneration, inflammation, and organ dysfunction. This entry, "cell-cell communication," describes a broad biological process and not a valid single therapeutic target, molecule, or receptor.

Other names

Cell signalingCell signallingIntercellular communicationCellular communicationCell interactionCCC