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Multiple immune cell surface antigens is a collective term for the diverse array of molecules expressed on immune cell membranes, including clusters of differentiation (CD) markers, major histocompatibility complex molecules, chemokine receptors, and other glycoproteins. These antigens allow immune cells to participate in critical biological functions such as antigen recognition, intercellular signaling, immune response regulation, and cell trafficking. Their differential expression is key to immune cell lineage identification (e.g., T cells, B cells, NK cells, macrophages) and to the selection of targeted therapies in cancer and chronic disease. Because the term refers to a heterogenous group rather than a single molecular entity, it is considered an incorrect or non-specific target designation for structured data applications.
Direct cellular cytotoxicity; Immune checkpoint blockade; Antibody-dependent cell-mediated cytotoxicity (ADCC); Complement activation; Immune modulation through receptor/ligand engagement
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