Cellular and neuronal membrane

The **cellular and neuronal membranes** are lipid bilayer structures that form the external boundaries of cells and neurons, creating a semipermeable barrier between the cell’s interior and its external environment[5][2]. In neurons, the membrane is crucial for maintaining ion gradients, membrane potential, and enabling electrical signaling. These membranes host a diverse array of **integral and peripheral membrane proteins**, such as ion channels, receptors, pumps (e.g., sodium-potassium pumps), and enzymes that facilitate vital cellular functions[1][2]. While many drugs act on membrane-associated proteins, the membrane itself is not a direct therapeutic target. Dysfunction of membrane components or composition can contribute to diseases, particularly neurodegenerative diseases like Alzheimer’s and Parkinson’s disease[3]. In summary, "cellular and neuronal membranes" denote a cellular structure rather than a specific, actionable target in pharmacology or drug discovery.

Other names

cell membraneplasma membraneneuronal membranebiological membrane