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Target intelligence / Profile preview
Cellular Communication Network Factor 2 mRNA (CCN2 mRNA)
- Target
- CCN2 mRNA
- Molecular classification
- mRNA
01
Overview
CCN2 messenger RNA (mRNA) encodes the protein known as cellular communication network factor 2, also widely referred to as connective tissue growth factor (CTGF). Overexpression of CCN2 mRNA/protein is associated with pathological fibrosis in various organs.
- Other names
- Connective Tissue Growth Factor mRNACTGF mRNA
02
Mechanism of action
N/A
03
Biological functions
Chondrocyte proliferation and differentiationCell adhesionRegulation of cell growthRegulation of collagen synthesis
04
Disease associations
Fibrosis (liver, kidney, lung, heart, skin, pancreas, intestine, eye tissues/cornea/sclera/conjunctivae/macula/choroid/sclera/vitreous body/lens/ciliary body/trabecular meshwork/schlemm's canal/anterior chamber angle/posterior capsule/subretinal space/peripapillary region/papillomacular bundle/fovea/parafovea/perifovea/peripheral retina/macular hole/macular edema/macular pucker/submacular hemorrhage/submacular fluid/submacular exudate/submacular neovascularization/choroidal neovascularization/chorioretinal scar/chorioretinal atrophy/drusen/hard exudates/cotton wool spots/flame-shaped hemorrhages/dot-blot hemorrhages/intraretinal microvascular abnormalities/neovascular glaucoma/neovascularization elsewhere/neovascularization at disc/neovascularization at iris/neovascularization at angle/rubeosis iridis/rubeosis faciei/rubeosis conjunctivae/rubeosis sclerae/rubeosis corneae/rubeosis retinae)Wound healing
05
Biomarkers
FibrosisWound healing
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