Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Cellular Communication Network Factor 4 (CCN4)
- Target
- CCN4
- Molecular classification
- Matricellular protein, Secreted protein, Growth factor
01
Overview
Cellular Communication Network Factor 4 (CCN4), also known as WISP1, is a secreted matricellular protein involved in various cellular processes including cell proliferation, migration, survival, and apoptosis. It plays a role in tissue repair, bone development, and is implicated in diseases such as cancer and fibrosis. CCN4's function is context-dependent, promoting tumor growth in some cancers but inhibiting metastasis in others. Its role in fibrosis involves enhancing extracellular matrix deposition. Therapeutic strategies are being explored to target CCN4, particularly in anti-fibrotic therapies.
- Other names
- WISP1WNT-inducible signaling pathway protein 1
02
Mechanism of action
Neutralizing CCN4 activity to reduce fibrosis or tumor growth. Modulation of integrin signaling.
03
Biological functions
Cell proliferationCell migrationCell survivalApoptosis regulationWound healingTissue repairOsteoblastic differentiation
04
Disease associations
Cancer progressionMetastasisFibrosisIdiopathic pulmonary fibrosisCardiac fibrosisAortic aneurysm
05
Biomarkers
Cancer progression markerMetastasis risk assessmentFibrotic disease prognosis
Beyond the preview
Go deeper on Cellular Communication Network Factor 4 (CCN4).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Cellular Communication Network Factor 4 (CCN4).