Target intelligence / Profile preview

Cellular Lipid Binding Agent (None)

Target
None
Molecular classification
Protein, Lipid Binding Protein, Intracellular Lipid Binding Protein, Apolipoprotein
01

Overview

Cellular lipid binding agents encompass a diverse group of proteins responsible for solubilizing hydrophobic molecules inside cells. They play pivotal roles in intracellular trafficking, signal transduction pathways involving bioactive lipids, regulation of gene expression via nuclear hormone receptors—and represent important targets for therapeutic intervention due to their involvement in health and disease processes ranging from metabolism to neurodegeneration.

Other names
Intracellular Lipid Binding ProteinsiLBPsFatty Acid Binding ProteinsFABPsApolipoproteinsApoEApoJ/ClusterinApoMSec14p
02

Mechanism of action

Modulation of lipid transport, metabolism, or signaling; interaction with nuclear receptors

03

Biological functions

Lipid metabolismSignal transductionNonvesicular transportRegulation of gene expressionLipid solubilizationIntracellular traffickingRedox state maintenance
04

Disease associations

Metabolic diseasesObesityDiabetesInflammationCancerNeurodegeneration
05

Interacting drugs

NSAIDs

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