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Target intelligence / Profile preview
Cellular organelle membrane
- Molecular classification
- Other
01
Overview
Cellular organelle membranes are lipid bilayer structures that surround internal organelles of eukaryotic cells—including nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, and more. These membranes share several features with the plasma membrane: primarily a phospholipid bilayer with embedded proteins that function in selective transport, signaling, structural integrity, and compartmentalization. Each organelle's membrane possesses unique proteins and lipid compositions suited to its biological role. Some organelles have a single membrane (e.g., endoplasmic reticulum, Golgi apparatus) while others have double membranes (e.g., nucleus, mitochondria, chloroplasts). Cellular organelle membranes are not, by themselves, considered drug targets but their integral proteins may serve as such.
- Other names
- Organelle membraneOrganelle lipid bilayerSubcellular membrane
02
Biological functions
Compartmentalization of cellular processesSelective transport of molecules (via membrane proteins/channels)Maintenance of organelle identity and environmentSignaling platform (hosting receptors/enzymes)Support and structural integrity
03
Disease associations
Other (some dysfunctions in organelle membranes can contribute to diseases, but "cellular organelle membrane" is not a direct therapeutic target)
04
Safety considerations
Disruption of organelle membranes can compromise cell viability across organsOff-target effects when targeting membrane proteins can damage essential cell functions
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