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Target intelligence / Profile preview
Cellular Redox Homeostasis (N/A)
- Target
- N/A
- Molecular classification
- Biological Process, Cellular Homeostasis
01
Overview
Cellular redox homeostasis refers to the dynamic process by which cells maintain a balance between reducing and oxidizing reactions. This balance is crucial for regulating numerous biological processes including metabolism, cell death, differentiation, immune responses and development. It involves multiple systems such as the glutathione system, thioredoxin system, NADPH-regenerating systems, and antioxidant enzymes. The Nrf2-Keap1 pathway is a central regulatory pathway. Disruption of this balance leads to oxidative stress, contributing to pathologies like cancer and degenerative diseases.
- Other names
- Redox balanceOxidation-reduction homeostasisCellular reducing environment maintenance
02
Mechanism of action
N/A
03
Biological functions
Metabolism regulationApoptosis controlImmune response modulationCell signaling regulationCell proliferation and viabilityProtection against oxidative damage
04
Disease associations
CancerNeurodegenerative diseaseCardiovascular diseaseAgingOther (implicated in various pathologies related to oxidative stress)
05
Safety considerations
Disruption leads to oxidative stress and cellular damage
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