Central and Peripheral Nervous System (CNS/PNS)

The Central and Peripheral Nervous System (CNS and PNS) constitutes the complex network of neurons and glial cells that regulates bodily functions and responses to the environment. The CNS, comprising the brain and spinal cord, serves as the primary integration center for processing information (StatPearls, 2023). The PNS consists of the nerves and ganglia outside the brain and spinal cord, connecting the CNS to limbs and organs to facilitate motor and sensory communication (NIH, 2024). This entry is classified as incorrect because it describes an entire anatomical system rather than a specific molecular target such as a receptor or enzyme. While thousands of drugs interact with components of these systems, the systems themselves are too broad to be considered individual therapeutic targets. Effective pharmacological intervention requires targeting specific molecular entities within these systems, such as ion channels or neurotransmitter receptors, to achieve therapeutic effects while minimizing systemic toxicity (Nature Reviews Drug Discovery, 2021).

Other names

Nervous systemCerebrospinal and peripheral nerves

Not applicable as this is an anatomical system rather than a specific molecular target.