Central nervous system inflamed tissue

Central nervous system inflamed tissue" refers to regions within the brain or spinal cord affected by inflammation, evidenced by infiltration of immune cells (e.g., T cells, B cells, microglia, macrophages), cytokine secretion, and tissue injury. It is a pathological state present in multiple diseases such as multiple sclerosis, trauma, stroke, or neurodegeneration. Its molecular makeup is heterogeneous, with various cells and molecules contributing to the inflammatory process and tissue damage.

Other names

inflamed CNS tissueneuroinflammationCNS inflammatory lesion

Mechanisms involve inhibition of components of the inflammatory cascade (e.g., cytokine blockade, inflammasome inhibition), not the tissue as a whole