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Centromere protein U pseudogene 1 (CENPUP1)

Target: CENPUP1
Molecular classification: Other (Pseudogene; not protein-coding, not a receptor, enzyme, transporter, or transcription factor)

Overview

Centromere protein U pseudogene 1 (CENPUP1) is a non-protein-coding pseudogene associated by nomenclature with Centromere protein U (CENPU), a key protein in centromere and kinetochore assembly. There is no evidence for biological function, molecular classification as a therapeutic target, disease association, or drug interactions for CENPUP1. The canonical protein-coding gene, Centromere protein U (CENPU), is essential for centromere function during mitosis and is involved in pathways affecting cell cycle progression and chromosome segregation, and is implicated in cancer biology.

Mechanism of action

None for CENPUP1.

Biological functions

None for CENPUP1, as pseudogenes are typically non-functional. For the actual protein-coding CENPU, functions include centromere assembly and kinetochore formation

Disease associations

None for CENPUP1. For the protein CENPU, associated disease roles include cancer (such as cervical cancer and familial hyperinsulinemic hypoglycemia)

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