Centrosomal protein 170B (CEP170B)

Centrosomal protein 170B (CEP170B) is a structural protein encoded by the CEP170B gene, located on chromosome 14. It is a component of the centrosome, a non-membranous organelle that serves as the primary microtubule organizing center in animal cells. CEP170B is involved in the organization of microtubules, which is critical for cell structure and function, especially during cell division and mitotic spindle formation. It has been associated with rare inherited diseases such as hypogonadotropic hypogonadism with or without anosmia and primary autosomal recessive microcephaly, suggesting a potential role in neurological and reproductive development. No direct evidence indicates that CEP170B is a therapeutic drug target, nor are there known drugs, clinical biomarkers, or specific safety challenges directly associated with modulation of this protein in clinical settings.

Other names

CEP170BCentrosomal protein 170BCEP170RFAM68CKIAA0284Cep170BCep170-related