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Centrosomal protein 57 kDa pseudogene

Molecular classification
Other (pseudogene)
01

Overview

The **centrosomal protein 57 kDa pseudogene** (ENSG00000227055) is a non-coding genomic element related to the functional centrosomal protein 57 kDa gene (CEP57)[1][2]. As a **pseudogene**, it does not encode a protein and has no direct biological or therapeutic function. Pseudogenes can sometimes regulate their parent genes by acting as competing endogenous RNAs or by modulating microRNA availability, but there is no evidence currently linking this specific pseudogene to such roles or to any disease states. The functional CEP57 gene encodes a centrosomal protein involved in microtubule stabilization and cell division, but such activities do not pertain to the pseudogene[1][10]. Summary of key issues: - **This is a pseudogene, not a protein-coding target.** - **Not a therapeutic target, drug interaction partner, or standard biomarker.** - **Common confusion arises because parent gene (CEP57) is protein-coding and disease-associated, but this does not apply to pseudogenes like ENSG00000227055.** For disease, functional protein, and therapeutic information, refer instead to the *functional* CEP57 gene (not the pseudogene)[10][6][8][14].

Other names
Centrosomal protein 57 kDa pseudogeneCEP57 pseudogeneCEP57PC10orf37C6orf182P
02

Biological functions

Other (pseudogenes generally do not have well-established biological functions; some pseudogenes have regulatory roles, but this is not established for ENSG00000227055)
03

Disease associations

Other (no established disease role for this pseudogene; its functional parental gene, CEP57, is involved in mosaic variegated aneuploidy syndrome and possibly cancer via centrosome dysfunction, but this does not apply to the pseudogene)

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